2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-13735B
    Quinacrine hydrochloride hydrate
    		Inhibitor 98.03%
    Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis.
    Quinacrine hydrochloride hydrate
  • HY-N0381
    Maackiain
    		Inhibitor 98.03%
    Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of  21.95 µg/mL. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells.
    Maackiain
  • HY-E70250
    Neocryptolepine
    		Inhibitor 98.05%
    Neocryptolepine (Cryptotackieine) has antiplasmodial activity. Neocryptolepine also shows antibacterial activity against Gram-positive bacteria (MIC < 100 μg/mL), and antifungal activity.
    Neocryptolepine
  • HY-18716
    Dextrorotation nimorazole phosphate ester
    		Inhibitor ≥98.0%
    Dextrorotation nimorazole phosphate ester is an anti-anaerobic and anti-parasitic agent.
    Dextrorotation nimorazole phosphate ester
  • HY-N0978
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid
    		Inhibitor ≥98.0%
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid is a Triterpenoid that isolated from the plant of Agrimonia Pilosa with antimalarial and antidiabetic activities.
    1,2,3,19-Tetrahydroxy-12-ursen-28-oic acid
  • HY-22044
    ICA
    		Inhibitor 99.92%
    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
    ICA
  • HY-B0806AS1
    Proguanil-d6 hydrochloride
    		Inhibitor 98.73%
    Proguanil-d6 hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor.
    Proguanil-d6 hydrochloride
  • HY-N7489
    β-Hederin
    		Inhibitor
    β-Hederin, a saponin isolated from Hedera helix L.(Araliaceae), possesses antileishmanial activity. β-Hederin exhibits IC50 values of 1.5 μM, 68 nM and 4.57 μM in L. Mexicana promastigotes, L. mexicana amastigotes and THP1 cells, respectively.
    β-Hederin
  • HY-12785S
    Albendazole sulfoxide-d3
    		Inhibitor 99.79%
    Albendazole sulfoxide-d3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.
    Albendazole sulfoxide-d<sub>3</sub>
  • HY-W049875
    Nitroxynil
    		Inhibitor 98.71%
    Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica.
    Nitroxynil
  • HY-B0318S2
    Metronidazole-d3
    		Inhibitor ≥99.0%
    Metronidazole-d3 is deuterium labeled Metronidazole.
    Metronidazole-d<sub>3</sub>
  • HY-N9320
    13,21-Dihydroeurycomanone
    		Inhibitor 98.11%
    13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
    13,21-Dihydroeurycomanone
  • HY-B1056
    Procodazole
    		Inhibitor 99.73%
    Procodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity.
    Procodazole
  • HY-U00295
    Melarsonyl
    		Inhibitor
    Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl
  • HY-153021
    NMT-IN-1
    		Inhibitor ≥98.0%
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
    NMT-IN-1
  • HY-N0924A
    (±)-Stylopine hydrochloride
    		99.66%
    (±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.
    (±)-Stylopine hydrochloride
  • HY-B1244S
    Dimetridazole-d3
    		Inhibitor 99.87%
    Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
    Dimetridazole-d<sub>3</sub>
  • HY-121002
    Alstonine
    		Inhibitor
    Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.
    Alstonine
  • HY-B0744C
    L-Eflornithine
    L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine
  • HY-117025
    Manzamine A
    		Inhibitor
    Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.
    Manzamine A
Parasite Isoform Comparison

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